Insulin replacement restores the vesicular secretory apparatus in the diabetic rat lacrimal gland
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چکیده
منابع مشابه
Relationship between the golgi apparatus, gerl, and secretory granules in acinar cells of the rat exorbital lacrimal gland
The method of secretory granuleformation in the acinar cells of the rat exorbital lacrimal gland was studied by electron microscope morphological and cytochemical techniques. Immature secretory granules at the inner face of the Golgi apparatus were frequently attached to a narrow cisternal structure similar to GERL as described in neurons by Novikoff et al. (Novikoff, P. M., A. B. Novikoff, N. ...
متن کاملThe lacrimal apparatus
The lacrimal apparatus The lacrimal system consists of: 1Secretory portion: Comprises the following: aThe lacrimal gland: Which is divided into palpebral (Aqueoussecretion) (near the temporal aspect of upper eyelid) and orbital (near the eyeball) lobes, and it is situated in the upper temporal angle of the orbit. bAccessory lacrimal glands: glands of Krause and glands of wolfring. cMeibomian gl...
متن کاملAge-dependent changes in rat lacrimal gland anti-oxidant and vesicular related protein expression profiles
PURPOSE Anti-oxidation and exocytosis are important for maintaining exocrine tissue homeostasis. During aging, functional and structural alterations occur in the lacrimal gland (LG), including oxidative damage to proteins, lipids, and DNA. The aims of the present study were to determine in the aging LG: a) the effects of aging on LG structure and secretory activity and b) changes in the express...
متن کاملLacrimal gland primary acinar cell culture: the role of insulin.
PURPOSE The goal of the present study was to establish a protocol for primary culture of lacrimal gland acinar cells (LGACs) and to assess the effect of adding insulin to the culture media. METHODS LGACs were isolated and cultured from lacrimal glands of Wistar male rats. The study outcomes included cell number, viability, and peroxidase release over time and in response to three concentratio...
متن کاملMalignant Lymphoma of Lacrimal Apparatus in the 7 Year Old Girl
Abstract Background Involvement of lacrimal apparatus by Non Hodgkin lymphoma as a first manifestation is extremely rare and only three cases have been reported in children. The purpose of this report is to determine the clinical characteristic of patient with primary involvement of lacrimal apparatus with lymphoma. Case presentation A 7-year-old girl with history of tearing, gradually prog...
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ژورنال
عنوان ژورنال: Arquivos Brasileiros de Oftalmologia
سال: 2015
ISSN: 0004-2749
DOI: 10.5935/0004-2749.20150041